Endocrine Abstracts

Background: Obesity can lead type 2 diabetes (T2D), however there are patients with obesity who present euglycemia. The mechanisms by which T2D appears have not been fully elucidated. Oncostatin m (OSM) is a proinflammatory cytokine, member of the IL-6 family, which is increased in obesity in mice and humans, and impairs browning in mice. Here, we aim at evaluating the potential role of OSM in the development of T2D in patients with obesity.Material and ...